Ama-V-vials ajwayele ukusetshenziselwa ukugcina amasampula noma izixazululo futhi avame ukusetshenziswa kumalabhorethri okuhlaziya kanye namakhemikhali e-biochemical. Lolu hlobo lwebhodlela lunendawo engezansi ene-groove emise okwe-V, engasiza ukuqoqa ngempumelelo nokukhipha amasampula noma izixazululo. Idizayini ye-V-bottom isiza ukunciphisa izinsalela futhi yandise indawo engaphezulu yesixazululo, okuzuzisa ukusabela noma ukuhlaziya. Ama-V-vials angasetshenziselwa izinhlelo zokusebenza ezahlukahlukene, njengokugcinwa kwesampula, i-centrifugation, nokuhlolwa kokuhlaziya.